Crop production in Mozambique is conducted across a wide range of environmental, soil and climate conditions, therefore, presenting different biophysical and agro-climatic challenges. In order to counteract these challenges, many farmers across the country practice intercropping as a means to reduce crop failure, improve soil health, food security and income. However, most crop models used to estimate crop yields were developed for monocrops rather than intercrops. Thus, the use of EO technology combined with crop models may represent a challenge in certain regions of the country where intercropping is the most prevalent farming practice. Other challenges that can be faced during the use of crop monitoring and yield forecasting include fragmented land, crop zoning based crop production that is not followed and the need of training.